Reference:[1]Mason H S, Lam D M, Arntzen C J. Expression of hepatitis B surface antigen in transgenic plants[J]. Proceedings of the National Academy of Sciences, 1992, 89(24): 11745-11749. [2]Holland T, Sack M, Rademacher T, et al. Optimal nitrogen supply as a key to increased and sustained production of a monoclonal full size antibody in BY 2 suspension culture[J]. Biotechnology and Bioengineering, 2010, 107(2): 278-289. [3]Unni S C, Soniya E V. Transgenic Cucumis sativus expressing the hepatitis B surface antigen[J]. Plant Molecular Biology Reporter, 2010, 28(4): 627-634. [4]He Z M, Jiang X L, Qi Y, et al. Assessment of the utility of the tomato fruit-specific E8 promoter for driving vaccine antigen expression[J]. Genetica, 2008, 133(2): 207-214. [5]Sunil Kumar G B, Ganapathi T R, Srinivas L, et al. Expression of hepatitis B surface antigen in potato hairy roots[J]. Plant Science, 2006, 170(5): 918-925. [6]Jani D, Meena L S, Rizwan ul Haq Q M, et al. Expression of cholera toxin B subunit in transgenic tomato plants[J]. Transgenic Research, 2002, 11(5): 447-454. [7]Moravec T, Schmidt M A, Herman E M, et al. Production of Escherichia coli heat labile toxin (LT) B subunit in soybean seed and analysis of its immunogenicity as an oral vaccine[J]. Vaccine, 2007, 25(9): 1647-1657. [8]Rosales-Mendoza S, Soria-Guerra R E, López Revilla R, et al. Ingestion of transgenic carrots expressing the Escherichia coli heat labile enterotoxin B subunit protects mice against cholera toxin challenge[J]. Plant Cell Reports, 2008, 27(1): 79-84. [9]Ashraf S, Singh P K, Yadav D K, et al. High level expression of surface glycoprotein of rabies virus in tobacco leaves and its immunoprotective activity in mice[J]. Journal of Biotechnology, 2005, 119(1): 1-14.[10]Yuan P, Li J S, Wu Y M. Progress, limitation and strategies in using plants to produce biopharmaceuticals[J]. Acta Prataculturae Sinica, 2013, 22(4): 283-299.[11]Hull A K, Criscuolo C J, Mett V, et al. Human-derived, plant produced monoclonal antibody for the treatment of anthrax[J]. Vaccine, 2005, 23(17): 2082-2086. [12]Ruggiero F, Exposito J Y, Bournat P, et al. Triple helix assembly and processing of human collagen produced in transgenic tobacco plants[J]. Febs Letters, 2000, 469: 132-136.[13]Nagaya S, Kawamura K, Shinmyo A, et al. The HSP terminator of Arabidopsis thaliana increases gene expression in plant cells[J]. Plant and Cell Physiology, 2010, 51: 328-332.[14]Anthonisen I L, Salvador M L, Klein U. Specific sequence elements in the 5′untranslated regions of rbcL and atpB gene mRNas stabilize transcripts in the chloroplast of Chlamydomonas reinhardtii [J]. RNA, 2001, 7(7): 1024-1033. [15]Huang L F, Liu Y K, Lu C A, et al. Production of human serum albumin by sugar starvation induced promoter and rice cell culture[J]. Transgenic Research, 2005, 14: 569-581.[16]Kang T J, Kim B G, Yang J Y, et al. Expression of a synthetic cholera toxin B subunit in tobacco using ubiquitin promoter and bar gene as a selectable marker[J]. Molecular Biotechnology, 2006, 32: 93-100.[17]Ko K, Tekoah Y, Rudd P M, et al. Function and glycosylation of plant-derived antiviral monoclonal antibody[J]. Proceedings of the National Academy of Sciences of the United States of America, 2003, 100: 8013-8018.[18]Zheng L L, Wang J, He L M, et al. Over-expression vector construction and genetic transformation of a protein kinase NtCIPK2 from Nitraria tangutorum[J]. Acta Prataculturae Sinica, 2013, 22(6): 223-229.[19]Ma J T, Wang Z L, Huang D G, et al. Application of genetic engineering in forage plants breeding[J]. Acta Prataculturae Sinica,2010,19(6):248-262.[20]Tao F, Ma J T, Tang Y X, et al. Functional analysis of drought-resistant transcription factors PeDREB2a and HhERF2 in Lotus corniculatus[J]. Acta Prataculturae Sinica, 2013, 22(3):250-258.[21]Liu J L, Zhang Z L, Wu Y M, et al. Establishment of an efficient Agrobacterium-mediated genetic transformation system of Lotus corniculatus[J]. Acta Prataculturae Sinica,2006,15(3):128-131. [22]Wally O, Jayaraj J, PunjaZ K. Comparative expression of β glucuronidase with five different promoters in transgenic carrot (Daucus carota L.) root and leaf tissues[J]. Plant Cell Reports, 2008, 27(2): 279-287. [23]Gallie D R, Lucas W J, Walbot V. Visualizing mRNA expression in plant protoplasts: factors influencing efficient mRNA uptake and translation[J]. The Plant Cell Online, 1989, 1(3): 301-311.[24]Zhe Z. 21st Century Plant Molecular Biology[M]. Beijing: Science Press,2000:121.[25]Mao L Q, Guo S D. Relationship betewwn Ω as well as the length of 3′poly (dA) and efficiency of gene expression[J]. Acta Botanica Sinica, 1998, 40(12): 1166-1168. [26]Shapiro R A, Herrick D, Manrow R E, et al. Determinants of mRNA stability in Dictyostelium discoideum amoebae: differences in poly (A) tail length, ribosome loading, and mRNA size cannot account for the heterogeneity of mRNA decay rates[J]. Molecular and Cellular Biology, 1988, 8(5): 1957-1969.[27]Wandelt C I, Khan M R I, Craig S, et al. Vicilin with carboxy-terminal KDEL is retained in the endoplasmic reticulum and accumulates to high levels in the leaves of transgenic plants[J]. The Plant Journal, 1992, 2(2): 181-192.[28]Sojikul P, Buehner N, Mason H S. A plant signal peptide hepatitis B surface antigen fusion protein with enhanced stability and immunogenicity expressed in plant cells[J]. Proceedings of the National Academy of Sciences, 2003, 100(5): 2209-2214. [29]Thanavala Y, Mahoney M, Pal S, et al. Immunogenicity in humans of an edible vaccine for hepatitis B[J]. Proceedings of the National Academy of Sciences of the United States of America, 2005, 102(9): 3378-3382.[30]Guo Q Q, Zhang Z L, Jiang S J, et al. Expression of an avian influenza virus (H5N1) hemagglutinin gene in transgenic Lotus corniculatus[J]. Plant Molecular Biology Reporter, 2012, 30(5): 1117-1124.参考文献:[1]Mason H S, Lam D M, Arntzen C J. Expression of hepatitis B surface antigen in transgenic plants[J]. Proceedings of the National Academy of Sciences, 1992, 89(24): 11745-11749. [2]Holland T, Sack M, Rademacher T, et al. Optimal nitrogen supply as a key to increased and sustained production of a monoclonal full-size antibody in BY-2 suspension culture[J]. Biotechnology and Bioengineering, 2010, 107(2): 278-289. [3]Unni S C, Soniya E V. Transgenic Cucumis sativus expressing the hepatitis B surface antigen[J]. Plant Molecular Biology Reporter, 2010, 28(4): 627-634. [4]He Z M, Jiang X L, Qi Y, et al. Assessment of the utility of the tomato fruit-specific E8 promoter for driving vaccine antigen expression[J]. Genetica, 2008, 133(2): 207-214. [5]Sunil Kumar G B, Ganapathi T R, Srinivas L, et al. Expression of hepatitis B surface antigen in potato hairy roots[J]. Plant Science, 2006, 170(5): 918-925. [6]Jani D, Meena L S, Rizwan-ul-Haq Q M, et al. Expression of cholera toxin B subunit in transgenic tomato plants[J]. Transgenic Research, 2002, 11(5): 447-454. [7]Moravec T, Schmidt M A, Herman E M, et al. Production of Escherichia coli heat labile toxin (LT) B subunit in soybean seed and analysis of its immunogenicity as an oral vaccine[J]. Vaccine, 2007, 25(9): 1647-1657. [8]Rosales-Mendoza S, Soria-Guerra R E, López-Revilla R, et al. Ingestion of transgenic carrots expressing the Escherichia coliheat-labile enterotoxin B subunit protects mice against cholera toxin challenge[J]. Plant Cell Reports, 2008, 27(1): 79-84. [9]Ashraf S, Singh P K, Yadav D K, et al. High level expression of surface glycoprotein of rabies virus in tobacco leaves and its immunoprotective activity in mice[J]. Journal of Biotechnology, 2005, 119(1): 1-14.[10]袁蓓,李京生,吴燕民.利用植物生产药用蛋白的进展、局限及应对策略[J]. 草业学报, 2013, 22(4): 283-299.[11]Hull A K, Criscuolo C J, Mett V, et al. Human-derived, plant-produced monoclonal antibody for the treatment of anthrax[J]. Vaccine, 2005, 23(17): 2082-2086. [12]Ruggiero F, Exposito J Y, Bournat P, et al. Triple helix assembly and processing of human collagen produced in transgenic tobacco plants[J]. Febs Letters, 2000, 469: 132-136.[13]Nagaya S, Kawamura K, Shinmyo A, et al. The HSP terminator of Arabidopsis thalianaincreases gene expression in plant cells[J]. Plant and Cell Physiology, 2010, 51: 328-332.[14]Anthonisen I L, Salvador M L, Klein U. Specific sequence elements in the 5′untranslated regions of rbcL and atpB gene mRNas stabilize transcripts in the chloroplast of Chlamydomonas reinhardtii[J]. RNA, 2001, 7(7): 1024-1033. [15]Huang L F, Liu Y K, Lu C A, et al. Production of human serum albumin by sugar starvation induced promoter and rice cell culture[J]. Transgenic Research, 2005, 14: 569-581.[16]Kang T J, Kim B G, Yang J Y, et al. Expression of a synthetic cholera toxin B subunit in tobacco using ubiquitin promoter and bar gene as a selectable marker[J]. Molecular Biotechnology, 2006, 32: 93-100.[17]Ko K, Tekoah Y, Rudd P M, et al. Function and glycosylation of plant-derived antiviral monoclonal antibody[J]. Proceedings of the National Academy of Sciences of the United States of America, 2003, 100: 8013-8018.[18]郑琳琳,王佳,贺龙梅,等. 唐古特白刺蛋白激酶基因NtCIPK2超表达载体构建及紫花苜蓿转化研究[J]. 草业学报, 2013, 22(6): 223-229.[19]马江涛,王宗礼,黄东光,等. 基因工程在牧草培育中的应用[J]. 草业学报,2010,19(6):248-262.[20]陶飞,马江涛,唐益雄,等. 抗逆转录因子在百脉根中的功能分析[J]. 草业学报, 2013, 22(3):250-258.[21]刘建利,张占路,吴燕民,等. 百脉根农杆菌快速高效遗传转化体系的建立[J]. 草业学报,2006,15(3):128-131. [22]Wally O, Jayaraj J, PunjaZ K. Comparative expression of β-glucuronidase with five different promoters in transgenic carrot (Daucus carota L.) root and leaf tissues[J]. Plant Cell Reports, 2008, 27(2): 279-287. [23]Gallie D R, Lucas W J, Walbot V. Visualizing mRNA expression in plant protoplasts: factors influencing efficient mRNA uptake and translation[J]. The Plant Cell Online, 1989, 1(3): 301-311.[24]朱祯. 走向21世纪的植物分子生物学[M]. 北京:科学出版社,2000:121.[25]毛立群, 郭三堆. Ω 序列和3′poly (dA) 长度与基因表达效率的关系[J]. 植物学报, 1998, 40(12): 1166-1168. [26]Shapiro R A, Herrick D, Manrow R E, et al. Determinants of mRNA stability in Dictyostelium discoideum amoebae: differences in poly (A) tail length, ribosome loading, and mRNA size cannot account for the heterogeneity of mRNA decay rates[J]. Molecular andCellular Biology, 1988, 8(5): 1957-1969.[27]Wandelt C I, Khan M R I, Craig S, et al. Vicilin with carboxy-terminal KDEL is retained in the endoplasmic reticulum and accumulates to high levels in the leaves of transgenic plants[J]. The Plant Journal, 1992, 2(2): 181-192.[28]Sojikul P, Buehner N, Mason H S. A plant signal peptide-hepatitis B surface antigen fusion protein with enhanced stability and immunogenicity expressed in plant cells[J]. Proceedings of the National Academy of Sciences, 2003, 100(5): 2209-2214. [29]Thanavala Y, Mahoney M, Pal S, et al. Immunogenicity in humans of an edible vaccine for hepatitis B[J]. Proceedings of the National Academy of Sciences of the United States of America, 2005, 102(9): 3378-3382.[30]Guo Q Q, Zhang Z L, Jiang S J, et al. Expression of an avian influenza virus (H5N1) hemagglutinin gene in transgenic Lotus corniculatus[J]. Plant Molecular Biology Reporter, 2012, 30(5): 1117-1124. |