Abstract: The fruit structures of 52 species and 5 varieties representing 26 genera from 4 subfamilies of Lamiaceae in northeasten China were deeply studied in the paper for the first time, using glycol methacrylate(GMA) sections and cells of the sclerenchyma region were separated for identifying the structure. The results show that the fruits of the family are mainly trigonous in shape, sometimes the edges of the fruits extend and form wing. The fruit surfaces are glabrous, reticulate or with hairs (including capitate or peltate glandular hairs, unicellular, uniseriate multicellular or branched non-glandular hairs). The areola of the fruit is mainly round, barely linear or V-shape. The pericarp could be divided into four parts: exocarp, mesocarp, sclerenchyma region and endocarp. The crystal exists in the sclerenchymatous region. The study completes the fruit anatomy of Lamiaceae in northeasten China and provides the basis for the further research of the fruit anatomy and taxonomy, and molecular systematics of Lamiaceae in China.