Changes in antimalarial compounds and antioxidation activities of Artemisia annua in response to fertilization

doi:10.11686/cyxb20140140

Abstract

Abstract: A pot experiment was carried out to study the changes in antimalarial compounds and antioxidation activities of Artemisia annua in response to fertilization to increase yields and to improve quality by rational fertilization. The plants were supplied with chemical fertilizer (CF),manure (M) or a mixture of chemical fertilizer and manure (CFM). The control (no fertilizer) was established in the same way except no fertilizer was added. Artemisic acid,dexyartemisinin,artemisinin,total flavonoids of leaves,stems and roots from A. annua were measured and then DPPH· (1,1-dipheny-l,2-picrylhyrazyl) scavenging rate of ethanol extracts during the bud period was analyzed. Fertilization promoted plant growth and the biomass was increased by 57.4% (CF),91.6% (M),and 92.3% (CFM) compared with the control. The concentration and accumulation of artemisic acid,deoxyartemisinin,artemisinin,and total flavonoids of A. annua changed in the following sequence: leaves>stems>roots,indicating that these compounds were formed and stored mainly in the leaves. Antioxidation activities expressed by the DPPH·scavenging rate,were also higher in leaves than those in roots and stems. There was a significant correlation between total flavonoids and the DPPH·scavenging rate. Fertilization,particularly CFM and M,decreased DPPH·scavenging rates but increased the concentration and accumulation of artemisic acid,dexyartemisinin,and artemisinin,even though total flavonoids changed little after fertilization. Therefore,it is necessary to advocate manure fertilization in the intensive cultivation of A. annua.

CLC Number:

S567.906

LUO Shi-qiong,SHI An-dong,YUAN Ling,HUANG Jian-guo. Changes in antimalarial compounds and antioxidation activities of Artemisia annua in response to fertilization[J]. Acta Prataculturae Sinica, 2014, 23(1): 339-345.

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